Calvin, on Romans 6:12 (“Therefore do not let sin reign in your mortal body, that you should obey it in its lusts.”)—
He does not say: ‘Let it not be,’ but ‘Let it not reign.’
So long as you live, sin must needs be in your members. At least let it be deprived of mastery.
Let not what it bids be done.
(Institutes, III.3.13)